Leah Bucholz talks about the intersection of two seemingly unrelated conditions: PTSD and Herpes Simplex Virus (HSV) in the context of VA disability. While these conditions may appear distinct, their connection, particularly through the influence of emotional stress, is significant. We aim to provide insights into the correlation between PTSD, emotional stress, and the reactivation of HSV, shedding light on the importance of holistic care for veterans.

Understanding Herpes Simplex Virus
Herpes Simplex Virus (HSV), comprising types 1 and 2, is a prevalent infection characterized by painful blisters and ulcers. Type 1 typically manifests on the lips, while type 2 primarily affects the genital region. However, variations in presentation exist, emphasizing the adaptability of the virus. HSV spreads through skin-to-skin contact and persists within nerve cells, alternating between dormant and active states. In the United States, about 50-80% of the population have oral Herpes Simplex Virus (HSV) and about 1 out of every 6 has genital herpes between the ages of 14-49.
Emotional Stress: A Trigger for HSV Reactivation
Emotional stress plays a pivotal role in the reactivation of HSV. The World Health Organization (WHO) highlights stress as a trigger, alongside factors such as illnesses, sun exposure, and hormonal changes. Stress-induced activation of cellular responses and disturbances in the immune system create favorable conditions for HSV resurgence.
Research by the University of North Carolina (UNC) School of Medicine found that stress may trigger HSV reactivation by activating the JNK protein pathway. Early findings suggest that stress triggers the release of more corticosteroids in the body, which may activate the JNK pathway in neurons. This stress-induced activation can lead to changes in viral DNA, potentially reactivating the herpes simplex virus (HSV) and causing symptoms like cold sores or encephalitis. Such findings underscore the need for stress management in individuals with HSV.
PTSD and Stress: A Nexus
Post-Traumatic Stress Disorder (PTSD), a psychiatric condition resulting from exposure to traumatic events, significantly impacts an individual’s psychological well-being. Veterans, in particular, are susceptible to PTSD due to their service-related experiences. The manifestations of PTSD extend beyond psychological symptoms, encompassing physiological changes and altered stress responses. Persistent stress, a hallmark of PTSD, serves as a catalyst for HSV reactivation, exacerbating the burden on affected individuals.
Scientific Insights
Recent studies shed light on the intricate relationship between stress, HSV reactivation, and mental health. Research published in Science Daily elucidates the molecular mechanisms underlying stress-induced HSV resurgence, emphasizing the role of cellular stress responses. Similarly, a prospective cohort study published in The Archives of Internal Medicine establishes a direct association between persistent stress and increased likelihood of HSV recurrence.
Another study highlights a significant relationship between herpesvirus reactivation and PTSD. It found that 78.1% of PTSD patients exhibited active herpesvirus infections.
These findings underscore the need for comprehensive care addressing both mental health and infectious diseases in veterans.
Clinical Implications and VA Disability
Recognizing the interplay between PTSD and Herpes Simplex Virus among veterans can be paramount. PTSD can weaken the immune system, increasing the likelihood of HSV reactivation and frequent outbreaks, which cause physical discomfort and added stress. This can worsen PTSD symptoms, creating a vicious cycle. Moreover, the stigma surrounding HSV may heighten feelings of shame and isolation, further intensifying the emotional challenges of living with PTSD.
Acknowledging the psychosomatic nature of these conditions is essential for accurate diagnosis and effective management. Healthcare providers must adopt a multidisciplinary approach, integrating stress management, antiviral therapies, and mental health support to improve the overall well-being of veterans.
VA Disability Ratings for PTSD and Herpes
The VA Disability Rating for PTSD is determined based on the severity of the condition and how much it impairs a veteran’s ability to function in daily life, including work and social settings. The VA uses a General Rating Formula for Mental Disorders to evaluate PTSD, which is rated at 0%, 10%, 30%, 50%, 70%, or 100% depending on the level of impairment.
The VA disability rating for herpes typically ranges from 0% to 60%, depending on the severity and frequency of outbreaks. It’s assessed under diagnostic code 7806, which evaluates skin conditions. The rating is based on factors like the extent of the affected skin, the need for systemic therapy (like corticosteroids or immunosuppressive drugs), and how frequently these treatments are required. Severe cases with widespread symptoms may qualify for a higher rating, while mild cases receive lower ratings.
Seeking Assistance
For veterans navigating the complexities of PTSD and Herpes Simplex Virus in the context of VA disability, seeking assistance is crucial. Consulting with accredited legal professionals, including accredited claims agents, attorneys, or Veterans Service Organizations (VSOs), can provide valuable guidance in filing disability claims. Additionally, engaging in open dialogue with healthcare providers fosters personalized care tailored to individual needs.
PTSD and Herpes Simplex Virus in VA Disability
In conclusion, the intersection of PTSD and Herpes Simplex Virus in VA disability underscores the intricate interplay between mental health and infectious diseases. Stress, a common denominator in both conditions, serves as a catalyst for HSV reactivation, exacerbating the burden on veterans. By acknowledging this relationship and adopting a holistic approach to care, healthcare providers can enhance the well-being of veterans, promoting resilience and recovery in the face of adversity.
Also read: Gout secondary to PTSD in VA Disability
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